Radioactive contamination is a pressing environmental issue that requires effective remediation techniques. Chemical and biological remediation methods have been proposed as potential solutions, but their comparative effectiveness remains unclear. This study seeks to address this gap by comparing the efficacy of these two remediation techniques in reducing radioactive contamination. The study involved a comprehensive review of existing literature on chemical and biological remediation techniques for radioactive contamination. The advantages and limitations of each technique was analyzed and their effectiveness in reducing radioactive contamination compared. Additionally, the practical application of these techniques in a real-world scenario were evaluated based on online data. The findings revealed that both chemical and biological remediation techniques have shown promise in reducing radioactive contamination. Chemical techniques, such as ion exchange and precipitation were observed as effective techniques in removing radioactive contaminants from soil and water. On the other hand, biological techniques, such as phytoremediation and microbial remediation, offer a sustainable and cost-effective approach to remediate radioactive contamination. However, the effectiveness of these techniques may vary depending on the specific characteristics of the contaminated site. Therefore, the he choice of remediation technique should be based on the specific characteristics of the contaminated site and the desired outcome. Based on our findings, a holistic approach that combines both chemical and biological remediation techniques to effectively address radioactive contamination is recommended. Furthermore, future research should focus on developing integrated remediation strategies that leverage the strengths of both techniques to achieve optimal results.